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Role of salivary matrix metalloproteinase-8 (MMP-8) in chronic periodontitis diagnosis

Namita Gupta,N.D. Gupta,Akash Gupta,Saif Khan,Neha Bansal

Frontiers of Medicine 2015, Volume 9, Issue 1,   Pages 72-76 doi: 10.1007/s11684-014-0347-x

Abstract: Any imbalance between the matrix metalloproteinases (MMPs) secreted by neutrophils and tissue inhibitorsThis study aimed to correlate salivary levels of MMP-8 and periodontal parameters of chronic periodontitisto establish MMP-8 as a noninvasive marker for the early diagnosis of chronic periodontitis.Around 3 ml of unstimulated and whole expectorated saliva was collected for MMP-8 estimation by ELISAusing Quantikine human total MMP-8 immunoassay kits.

Keywords： matrix metalloproteinase-8     chronic periodontitis     pocket probing depth     clinical attachment level     gingival    

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Zeolitic imidazolate framework-8 (ZIF-8) for drug delivery: A critical review

Simin Feng, Xiaoli Zhang, Dunyun Shi, Zheng Wang

Frontiers of Chemical Science and Engineering 2021, Volume 15, Issue 2,   Pages 221-237 doi: 10.1007/s11705-020-1927-8

Abstract: Zeolitic imidazolate framework-8 (ZIF-8), composed of Zn ions and imidazolate ligands, is a class ofaspects ranging from synthesis methods, property characterization to potential applications of ZIF-8.This review focuses on the recent development of ZIF-8 synthesis methods and its promising applicationsThe potential risks of using ZIF-8 for drug delivery are also summarized.

Keywords： zeolitic imidazolate framework-8 (ZIF-8)     synthesis methods     applications     drug delivery    

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Adenovirus-mediated tissue inhibitor of metalloproteinase-3 gene transfection inhibits rabbit intervertebral

Xudong YU MM, Zengwu SHAO MD, Liming XIONG MD, Weiwei XU MM, Hezhong WANG MM, Huifa XU MM,

Frontiers of Medicine 2009, Volume 3, Issue 4,   Pages 415-420 doi: 10.1007/s11684-009-0072-z

Abstract: to investigate the inhibitory effects of recombinant adenovirus vector carrying tissue inhibitor of metalloproteinaseO-Fast green staining and type II collagen staining demonstrated better reserved integrity of disc matrixRAdTIMP-3 can effectively protect the matrix of rabbit intervertebral disc against overloading-induced

Keywords： tissue inhibitor of metalloproteinase-3     intervertebral disc     rabbit     gene therapy    

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Lymphatic metastasis is related to the epithelial-mesenchymal transition and expressions of VEGF, MMP-9, and COX-2 in breast cancer

Lihui WANG, Lianhong LI, Shen LV, Shujun FAN, Li ZHAN, Bo WANG, Zhong ZHANG

Frontiers of Medicine 2009, Volume 3, Issue 2,   Pages 164-170 doi: 10.1007/s11684-009-0038-1

Abstract: expressions of E-cadherin (E-Cad), N-cadherin (N-Cad), vascular endothelial cell growth factor (VEGF), matrixmetalloproteinase-9 (MMP-9), cyclooxygenase-2 (COX-2), and CD34 were examined in 74 cases of breast

Keywords： epithelial-mesenchymal transition     vascular endothelial cell growth factor     matrix metalloproteinase-9    

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Protective efficacy of vaccination with NcMIC3 and NcMIC8 against

Taotao ZHANG, Xiao ZHANG, Qun LIU, Jianhai XU, Jing LIU

Frontiers of Agricultural Science and Engineering 2019, Volume 6, Issue 2,   Pages 188-196 doi: 10.15302/J-FASE-2019253

Abstract: Several studies have indicated that MIC3 and MIC8 are important adhesion factors and potential vaccinestudy, we evaluated the protective efficacy of recombinant proteins and DNA vaccines of NcMIC3 and NcMIC8.BALB/c mice were immunized with rNcMIC3, rNcMIC8, pcDNA3.1-NcMIC3 and pcDNA3.1-NcMIC8 respectively, andIn addition, mice immunized with rNcMIC3 and rNcMIC8 a had lower parasite burden in brain tissue comparedThese results demonstrate that rNcMIC3 and rNcMIC8 could induce humoral and Th2-type immune response,

Keywords： NcMIC3     NcMIC8     Neospora caninum     vaccination    

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The Undersea Tunnel on Qingdao Metro Line 8

Weiguo He, Peng Liu

Engineering 2018, Volume 4, Issue 2,   Pages 167-169 doi: 10.1016/j.eng.2018.03.012

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Development of 8-inch Key Processes for Insulated-Gate Bipolar Transistor Article

Guoyou Liu,Rongjun Ding,Haihui Luo

Engineering 2015, Volume 1, Issue 3,   Pages 361-366 doi: 10.15302/J-ENG-2015043

Abstract:

Based on the construction of the 8-inch fabrication line, advanced process technology of 8-inch wafergreat-leap forward technological development for the manufacturing of high-voltage IGBT from 6-inch to 8-

Keywords： insulated-gate bipolar transistor (IGBT)     high power density     trench gate     8-inch     rail transportation    

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Prohibitin regulates mTOR pathway via interaction with FKBP8

Jiahui Zhang, Yanan Yin, Jiahui Wang, Jingjing Zhang, Hua Liu, Weiwei Feng, Wen Yang, Bruce Zetter, Yingjie Xu

Frontiers of Medicine 2021, Volume 15, Issue 3,   Pages 448-459 doi: 10.1007/s11684-020-0805-6

Abstract: FK506 binding protein 8 (FKBP8) is an intrinsic inhibitor of mTOR kinase that also exerts an anti-apoptoticproteomic analysis that the mitochondrial protein prohibitin 1 (PHB1) specifically interacts with FKBP8.inhibited the proliferation of ovarian cancer cells and the mTOR signaling pathway, whereas the FKBP8Moreover, concomitant with these changes, the interaction between FKBP8 and mTOR substantially increasedCollectively, our finding highlights PHB1 as a potential regulator of FKBP8 because of its subcellular

Keywords： prohibitin 1     FKBP8     mTOR     cell proliferation     cancer    

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Decellularized extracellular matrix mediates tissue construction and regeneration

Frontiers of Medicine 2022, Volume 16, Issue 1,   Pages 56-82 doi: 10.1007/s11684-021-0900-3

Abstract: Contributing to organ formation and tissue regeneration, extracellular matrix (ECM) constituents provideContaining the crucial traits of the cellular microenvironment, ECM substitutes mediate cell–matrix interactions

Keywords： decellularized extracellular matrix     3D culture     organoids     tissue repair    

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Predictive values of plasma TNFα and IL-8 for intracranial hemorrhage in patients with acute promyelocytic

Frontiers of Medicine 2022, Volume 16, Issue 6,   Pages 909-918 doi: 10.1007/s11684-021-0890-1

Abstract: Results showed that tumor necrosis factor α and interleukin 8 (IL-8) were vital in distinguishing patientsFinally, in-vitro and in-vivo experimental evidence were provided to show that IL-8 influenced

Keywords： acute promyelocytic leukemia     intracranial hemorrhage     cytokines     biomarker    

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Perspective of mixed matrix membranes for carbon capture

Shinji Kanehashi, Colin A. Scholes

Frontiers of Chemical Science and Engineering 2020, Volume 14, Issue 3,   Pages 460-469 doi: 10.1007/s11705-019-1881-5

Abstract: Mixed matrix membranes (MMMs) have a composite structure that consists of polymers and fillers, therefore

Keywords： membranes     polymeric     mixed matrix     impurities    

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IRF4 and IRF8 expression are associated with clinical phenotype and clinico-hematological response to

Frontiers of Medicine 2022, Volume 16, Issue 3,   Pages 403-415 doi: 10.1007/s11684-021-0858-1

Abstract: We have previously shown that interferon regulatory factor-8 (IRF8) and IRF4 serve as tumor suppressorsIn this study, we evaluated the expression of IRF4 and IRF8 and the JAK2V617F mutant allele burden inNegative correlations between the JAK2V617F allele burden and the expression of IRF8 (P <0.05)At 3 months, patients in the CR group showed high IRF4 and IRF8 expression compared with patients inOur data indicate that the expression of IRF4 and IRF8 was associated with the MPN phenotype, which may

Keywords： myeloproliferative neoplasms     IRF4     IRF8     hydroxyurea     essential thrombocythemia    

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Parametric study on the mixed solvent synthesis of ZIF-8 nano- and micro-particles for CO adsorption:

Alireza Hadi, Javad Karimi-Sabet, Abolfazl Dastbaz

Frontiers of Chemical Science and Engineering 2020, Volume 14, Issue 4,   Pages 579-594 doi: 10.1007/s11705-018-1770-3

Abstract: The room temperature synthesis of ZIF-8 micro- and nano-particles was investigated using a mixed methanol-waterZIF-8 particles of good quality and high crystallinity were obtained.Response surface methodology was used to determine the effect of the synthesis conditions on the ZIF-8method to size-controlled synthesis of ZIF-8 particles.adsorption and the mid-sized ZIF-8 particles had the highest adsorption capacity.

Keywords： metal organic frameworks     zeolitic imidazolate frameworks     ZIF-8     response surface methodology     Box Behnken    

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Gene therapy for hemophilia B mice with scAAV8-LP1-hFIX

Wei Lu,Qingzhang Zhou,Hao Yang,Hao Wang,Yexing Gu,Qi Shen,Jinglun Xue,Xiaoyan Dong,Jinzhong Chen

Frontiers of Medicine 2016, Volume 10, Issue 2,   Pages 212-218 doi: 10.1007/s11684-016-0438-y

Abstract: Self-complementary adeno-associated virus serotype 8 (scAAV8), a non-human primate AAV featuring lowliver-specific promoter-1 (LP1) was inserted and mutant human FIX Arg338Ala was introduced into plasmid scAAV8-LP1 to develop an optimized AAV8 vector that expresses human clotting factor FIX (hFIX).The efficiency of scAAV8-LP1-hFIX administered through normal systemic injection or hydrodynamic injection

Keywords： hemophilia B     AAV8     hFIX     gene therapy    

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A highly selective fluorescent probe for real-time imaging of UDP-glucuronosyltransferase 1A8 in living

Frontiers of Chemical Science and Engineering 2022, Volume 16, Issue 1,   Pages 103-111 doi: 10.1007/s11705-021-2064-8

Abstract: was developed based on boron-dipyrromethene (BODIPY) with high sensitivity for the detection of UGT1A8.dependent fluorescence signal with a good linear relationship with UGT1A8 concentration.perfect biocompatibility and cell permeability, BDMP was successfully used to image endogenous UGT1A8In addition, BDMP could also be used to visualize UGT1A8 in tumor tissues.These results suggested that BDMP is a promising molecular tool for the investigation of UGT1A8-mediated

Keywords： UDP-glucuronosyltransferase 1A8     fluorescent probe     subtype selectivity     fluorescence imaging    

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Title Author Date Type Operation

Role of salivary matrix metalloproteinase-8 (MMP-8) in chronic periodontitis diagnosis

Namita Gupta,N.D. Gupta,Akash Gupta,Saif Khan,Neha Bansal

Journal Article

Zeolitic imidazolate framework-8 (ZIF-8) for drug delivery: A critical review

Simin Feng, Xiaoli Zhang, Dunyun Shi, Zheng Wang

Journal Article

Adenovirus-mediated tissue inhibitor of metalloproteinase-3 gene transfection inhibits rabbit intervertebral

Xudong YU MM, Zengwu SHAO MD, Liming XIONG MD, Weiwei XU MM, Hezhong WANG MM, Huifa XU MM,

Journal Article

Lymphatic metastasis is related to the epithelial-mesenchymal transition and expressions of VEGF, MMP-9, and COX-2 in breast cancer

Lihui WANG, Lianhong LI, Shen LV, Shujun FAN, Li ZHAN, Bo WANG, Zhong ZHANG

Journal Article

Protective efficacy of vaccination with NcMIC3 and NcMIC8 against

Taotao ZHANG, Xiao ZHANG, Qun LIU, Jianhai XU, Jing LIU

Journal Article

The Undersea Tunnel on Qingdao Metro Line 8

Weiguo He, Peng Liu

Journal Article

Development of 8-inch Key Processes for Insulated-Gate Bipolar Transistor

Guoyou Liu,Rongjun Ding,Haihui Luo

Journal Article

Prohibitin regulates mTOR pathway via interaction with FKBP8

Jiahui Zhang, Yanan Yin, Jiahui Wang, Jingjing Zhang, Hua Liu, Weiwei Feng, Wen Yang, Bruce Zetter, Yingjie Xu

Journal Article

Decellularized extracellular matrix mediates tissue construction and regeneration

Journal Article

Predictive values of plasma TNFα and IL-8 for intracranial hemorrhage in patients with acute promyelocytic

Journal Article

Perspective of mixed matrix membranes for carbon capture

Shinji Kanehashi, Colin A. Scholes

Journal Article

IRF4 and IRF8 expression are associated with clinical phenotype and clinico-hematological response to

Journal Article

Parametric study on the mixed solvent synthesis of ZIF-8 nano- and micro-particles for CO adsorption:

Alireza Hadi, Javad Karimi-Sabet, Abolfazl Dastbaz

Journal Article

Gene therapy for hemophilia B mice with scAAV8-LP1-hFIX

Wei Lu,Qingzhang Zhou,Hao Yang,Hao Wang,Yexing Gu,Qi Shen,Jinglun Xue,Xiaoyan Dong,Jinzhong Chen

Journal Article

A highly selective fluorescent probe for real-time imaging of UDP-glucuronosyltransferase 1A8 in living

Journal Article